Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but t
Expression of HuR in Merkel cell carcinoma and in normal skin
✍ Scribed by Virve Koljonen; Tom Böhling; Caj Haglund; Ari Ristimäki
- Book ID
- 111242201
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 241 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0303-6987
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Merkel cell carcinoma is a rare, aggressive neuroendocrine tumor of the skin with a predisposition for local regional and distant spread. Radiotherapy after wide local excision has improved local control, but distant spread continues to be a significant problem. This is an update of our experience i
Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but t