## Abstract ## BACKGROUND: Tumor‐associated differentially expressed gene‐12 (TADG‐12) is a serine protease recently found highly differentially expressed in epithelial ovarian cancer. The goal of this study was to identify potential immunogenic peptides derived from TADG‐12 for immunotherapy of o
✦ LIBER ✦
Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes
✍ Scribed by Chungwen Wei; Eugene Storozynsky; A. J. McAdam; Kun-Yun Yeh; Brian R. Tilton; Richard A. Willis; Richard K. Barth; R. John Looney; Edith M. Lord; J. G. Frelinger
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 171 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0340-7004
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To generate non-small cell lung cancer (NSCLC)-reactive lymphocytes, we transfected an HLA-A2-expressing human NSCLC line (1355) with the cDNA encoding the lymphocyte co-stimulatory molecule CD80. Following selection in G418, 1355.7 demonstrated stable cell-surface expression of CD80. Allogeneic mix