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Expression of human P140TRK receptors in P140TRK- deficient PC12/endothelial (PpC12EN) cells results in nerve growth factor (NGF)-induced signal transduction and DNA synthesis

โœ Scribed by P. Lazarovici; H. Jiang; V. Movsesyan; D.W. Fink Jr.; M. Fasler; M. Whalin; M. Monshipouri; G. Dickens; P. Lelkes; G. Guroff


Book ID
117476330
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
28 KB
Volume
237
Category
Article
ISSN
0304-3940

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Expression of human p140trk receptors in
โœ Hao Jiang; Vilen Movsesyan; Donald W. Fink; Jr.; Monika Fasler; Michael Whalin; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 386 KB ๐Ÿ‘ 1 views

Nerve growth factor (NGF) regulates proliferation, differentiation, and survival of sympathetic and sensory neurons through the tyrosine kinase activity of its receptor, p140 trk . These biological effects of NGF depend upon the signal-mediating function of p140 trk substrates which are likely to di