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Expression of human clotting factor IX mediated by recombinant lentiviral vector in cultured cells and hemophilia B mice

✍ Scribed by Huanzhang Zhu; Xiaoguang Chen; Feng Li; Juli Gong; Jinglun Xue


Publisher
Springer
Year
2003
Tongue
English
Weight
463 KB
Volume
48
Category
Article
ISSN
1001-6538

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## Abstract ## Background A gene therapy delivery system based on microcapsules enclosing recombinant cells engineered to secrete a therapeutic protein was explored in this study. In order to prevent immune rejection of the delivered cells, they were enclosed in non‐antigenic biocompatible alginat