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Expression of human Alzheimer amyloid precursor protein in insect cells

✍ Scribed by Narayan Ramakrishna; Pothana Saikumar; Anna Potempska; Henryk M. Wisniewski; David L. Miller


Book ID
115764361
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
871 KB
Volume
174
Category
Article
ISSN
0006-291X

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One of the pathological lesions in Alzheimer's disease (AD) is the amyloid or senile plaque. The plaque core is predominantly made up of amyloid beta peptide (AP), a 42-43 amino acid peptide derived from amyloid precursor protein (APP). APP is a membrane bound glycoprotein which is expressed ubiquit