Expression of HLA-DR and OKT6 antigens on keratinocytes and dendritic cells in pemphigus
β Scribed by C. Picut; J. Meunier; C. Lee; R. Lewis
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 962 KB
- Volume
- 279
- Category
- Article
- ISSN
- 0340-3696
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π SIMILAR VOLUMES
In order to determine precisely the cellular density of surface molecules that are critical for antigen presentation in human epidermis, we utilized a quantitative immunofluorescence indirect assay and performed flow cytometric analysis of human epidermal cell (EC) suspensions. We first demonstrated
## associated antigens Recombinant interferon-y (IFN-y) induced the expression of HLA-DR when added to the culture medium of HLA-DR-melanoma cell lines. In addition, IFN-y induced the expression of another class I1 antigen, HLA-DC, on a HLA-DR' and -DCmelanoma cell line and to a lower level on a -