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Expression of hepatocyte growth factor and its receptor c-met in human leukemia-lymphoma cell lines

โœ Scribed by E Pons; C.C Uphoff; H.G Drexler


Book ID
114119481
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
187 KB
Volume
22
Category
Article
ISSN
0145-2126

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The c-met proto-oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a potent mitogen and motogen for epithelial cells. Because of its profound effects on cell growth and motility, HGF may be important in the development of cancer metastases in hepatocellular carcinoma (

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mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for