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Expression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Breast Carcinoma

โœ Scribed by Yasuhiro Ito; Tsutomu Takeda; Shigeki Higashiyama; Shinzaburo Noguchi; Nariaki Matsuura


Book ID
110293199
Publisher
Springer US
Year
2001
Tongue
English
Weight
122 KB
Volume
67
Category
Article
ISSN
0167-6806

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## Abstract ## BACKGROUND. Cleavage of membraneโ€anchored heparinโ€binding epidermal growth factorโ€like growth factor (proHBโ€EGF) yields a soluble HBโ€EGF isoform (sHBโ€EGF), which is an activating epidermal growth factor receptor (EGFR) ligand and a Cโ€terminal fragment HBโ€EGFโ€C acting directly in the