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Expression of glial cell line-derived neurotrophic factor (GDNF) and GDNF family receptor α1 in mouse taste bud cells after denervation

✍ Scribed by Masako Takeda; Yuko Suzuki; Nobuko Obara; Nobuhiko Uchida; Kentaro Kawakoshi

Book ID
109005710
Publisher
Springer Japan
Year
2005
Tongue
English
Weight
199 KB
Volume
80
Category
Article
ISSN
1447-6959

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Human SK-N-AS neuroblastoma and U-87MG glioblastoma cell lines were found to secrete relatively high levels of glial cell line-derived neurotrophic factor (GDNF). In response to growth factors, cytokines, and pharmacophores, the two cell lines differentially regulated GDNF release. A 24-hr exposure