Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine; comparison to the liver
✍ Scribed by Monica Lindell; Matti Lang; Hans Lennernäs
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 983 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0378-7966
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Peroxidase activity was partially purified from neonatal (3 to 6 days old) rat skin. The membrane-bound peroxidase activity was extracted with 0.5 M calcium chloride and was monitored spectrophotometrically at 470 nm with 2-methoxyphenol (guaiacol) and hydrogen peroxide as substrates. Subcellular di
Cytochromes P450 (CYPs) and p-glycoproteins (Pgps) are believed to play important roles in drug absorption, metabolism, and elimination. Numerous drugs and environmental chemicals can modulate expression of these two classes of genes in different species. The present study investigated the effect of