Up-regulation of Fas and Fas ligand and excessive apoptosis of bronchiolar and alveolar epithelial cells were identiยฎed in bleomycin-induced pulmonary ยฎbrosis in mice. This study hypothesized that apoptosis-regulatory genes other than FasยฑFas ligand, such as p53, p21 (Waf1/Cip1), bcl-2, bcl-x, and b
Expression of GABAergic system in pulmonary neuroendocrine cells and airway epithelial cells in GAD67-GFP knock-in mice
โ Scribed by Yasuaki Yabumoto; Masahito Watanabe; Yuko Ito; Kentaro Maemura; Yoshinori Otsuki; Yumi Nakamura; Yuchio Yanagawa; Kunihiko Obata; Katsuya Watanabe
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 453 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0918-4287
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Recent data have identified IL-9 as a key cytokine in determining susceptibility to asthma. These data are supported by the finding that allergen-exposed IL-9-transgenic mice exhibit many features that are characteristic of human asthma (airway eosinophilia, elevated serum IgE and bronchial hyperres
## Abstract Mucus hypersecretion is an important characteristic feature of the pathogenesis of allergy. Although interleukin (IL)โ4 is known to be an inflammatory mediator in respiratory diseases, the mechanism by which ILโ4 induces __MUC5AC__ gene expression has not been fully explored. The aim of
## Abstract Lysozyme is a major component of airway epithelial secretions, acts as cationic antiโmicrobial protein for innate immunity. Although lysozyme plays an important role in airway defense and is a key component of airway secretions under inflammatory conditions, little is understood about t