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Expression of fibronectin and its integrin receptor α5β1 in canine mammary tumours

✍ Scribed by L. Peña; A. Nieto; M.D. Perez Alenza; A. Rodriguez; M.A. Sanchez; M. Castaño

Book ID
116052819
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
635 KB
Volume
57
Category
Article
ISSN
0034-5288

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Cytofluorimetric and reverse-transcription polymerase chain reaction (RT-PCR) analysis showed that adriamycinresistant (ADR R ), but not sensitive (WT), MCF-7 human mammary carcinoma cell lines express a4b1 and a5b1 integrins. ADR R cells adhere to fibronectin (FN), and only a5b1 is involved in cell