Expression of epidermal growth factor receptors in human lung tumors
โ Scribed by David L. Hwang; Yee-chaw Tay; Shu S. Lin; Arye Lev-Ran
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 431 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Background: Over-expression of human epidermal growth factor receptor (egfr) is associated with a variety of human malignancies, including head and neck cancer. it has also been studied for its effect on cancer cell responses to chemotherapy. to accurately measure changes in egfr expression that
In C3H/10T1/2 murine fibroblasts, overexpression of both c-Src and the human epidermal growth factor (EGF) receptor 1 (HER1) is required for detection of stable complexes between the two molecules and results in hyperactivation of the receptor and synergistic increases in tumor formation in nude mic
The roles of growth factors in mouse lung neoplasia were investigated by examining receptors for platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) in epithelial cell lines. Whereas nontumorigenic lung cells expressed mRNA and protein for PDGF receptor (PDGFR)-a, PDGFR-b, and EG
Six different ligands of the epidermal-growth-factor receptor (EGFR) have been identified in the past. In some cervical squamous-cell carcinomas, an increased amount of proteins binding to the EGFR has been reported. In order to identify the mRNA of EGFR ligands (EGFRL), which might be overexpressed