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Expression of endothelial nitric oxide synthase protein is not necessary for mechanical strain-induced nitric oxide production by cultured osteoblasts

✍ Scribed by V. Das-Gupta, R. A. Williamson, A. A. Pitsillides

Book ID: 118780380
Publisher: Springer-Verlag
Year: 2012
Tongue: English
Weight: 697 KB
Volume: 23
Category: Article
ISSN: 0937-941X
DOI: 10.1007/s00198-012-1957-2

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## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN