DNAs from peripheral blood mononuclear cells (PBMCs) of 21 patients with multiple sclerosis (MS), 1 patient with tropical spastic paraparesis (TSP) as well as DNAs from brain and spinal cord of 5 MS cases and 3 controls were examined for human T-cell lymphotropic virus (HTLV)-related sequences by po
β¦ LIBER β¦
Expression of endogenous retroviruses in blood mononuclear- cells and brain tissue from multiple sclerosis patients
β Scribed by H. B. Rasmussen; C. Geny; L. Deforges; H. Perron; W. Tourtelotte; A. Heltberg; J. Clausen
- Book ID
- 109336723
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 797 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0001-6314
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## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cellβmediated autoimmune disease. Tβbet has been identified as a key transcription factor for the development of Th1 cells and the inducti