Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients
β Scribed by Monique M. Nijkamp; Paul N. Span; Ilse J. Hoogsteen; Albert J. van der Kogel; Johannes H.A.M. Kaanders; Johan Bussink
- Book ID
- 118498001
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 726 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0167-8140
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The cell-cell adhesion molecule E-cadherin has been shown to suppress invasive growth of epithelial cells in vitro, and loss of its expression is thought to be important in invasion and metastatic potential of epithelial tumors in vivo. We retrospectively studied the level of E-cadherin expression i
## Abstract Comparative genomic hybridization (CGH) was used to detect chromosomal changes during metastasis formation of head and neck squamous cell carcinomas (HNSCCs). In total, 92 tumors of 54 patients were investigated. In 34 of these, the metastases were compared to the corresponding primary