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Expression of distinct conformations of free HLA-Cw4 heavy chains in transfected neuroblastoma cells

โœ Scribed by Anna Marozzi; Raffaella Meneveri; Claudio De Santis; Piera Robbioni; Elena Molteni; Alberto Beretta; Antonio G. Siccardi; Enrico Ginelli

Book ID
105575874
Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
694 KB
Volume
43
Category
Article
ISSN
0093-7711

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Membrane expression of HLA-Cw4 free chai
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice
โœ Alessandro Aiuti; Pietro Forte; Luca Simeoni; Maddalena Lino; Laura Pozzi; Andre ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 932 KB

Transgenic mice were produced in which human HLA-Cw4 is stably integrated, behaves as a single Mendelian trait, and, being under the transcriptional control of human CD2, is selectively and efficiently expressed in T lymphocytes. These mice were used as a model system to determine whether HLA-type C