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Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary

โœ Scribed by So Yeon Park; Hee Sung Kim; Eun Kyung Hong; Woo Ho Kim


Book ID
117818668
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
594 KB
Volume
33
Category
Article
ISSN
1532-8392

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A series of 33 tumor cases (13 fine-needle aspirates and 20 effusion specimens) were evaluated for the expression of two cytokeratin (CK) subtypes; CK 20, expressed primarily in tumors of the GI tract, mucinous ovarian tumors and transitional cell carcinomas, and CK 7, found chiefly in non-GI tract

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## BACKGROUND. Metastatic adenocarcinoma in the liver with an unidentified primary tumor site is a common clinical problem. Pathologists often are asked to identify the primary tumor site. The histologic picture itself usually is not helpful, because the histology may be similar in the metastases