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Expression of cyclin D1 and GSK-3β and their predictive value of prognosis in squamous cell carcinomas of the tongue

✍ Scribed by H Goto; K Kawano; I Kobayashi; H Sakai; S Yanagisawa

Book ID: 114393865
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 344 KB
Volume: 38
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(01)00121-x

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## Background: Abnormalities of chromosome band 11q13 are frequent in squamous cell carcinoma of the head and neck (scchn). the oncogene ccnd1 is located at 11q13 and encodes cyclin d1, a cell cycle-regulating protein. the authors investigated the clinical relevance and associations between amplifi