Expression of costimulatory molecules B7/CD28 in systemic lupus erythematosus
β Scribed by Hu Shaoxian; Tao Deding; He Peigen
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- Chinese
- Weight
- 286 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0510-9752
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Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,
## Abstract This study attempted to estimate soluble CD4(sCD4)/CD8(sCD8) molecules in active systemic lupus erythematosus (SLE) patients. Measurements were made by solidβphase enzymeβlinked immunosorbent assay. sCD8 or sCD4 molecules were significantly increased in the patients as compared to contr