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Expression of constitutively active p21H-rasval12 in postmitotic pyramidal neurons results in increased dendritic size and complexity

✍ Scribed by Alán Alpár; Kirstin Palm; Andreas Schierwagen; Thomas Arendt; Ulrich Gärtner

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
607 KB
Volume
467
Category
Article
ISSN
0021-9967

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Constitutive expression of p21H-Rasval12
Constitutive expression of p21H-Rasval12 in neurons induces increased axonal size and dendritic microtubule density in vivo
✍ Gudrun Seeger; Ulrich Gärtner; Max Holzer; Thomas Arendt 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 515 KB

## Abstract The small G protein p21Ras is a key signal transducer mediating cellular growth and proliferation responses to extracellular stimuli. We investigated by electron microscopy the effects of augmented p21Ras activity on neuronal processes and microtubule arrangement in vivo. We used transg