Expression of connexin 43 in human testis
โ Scribed by K. Steger; Frank Tetens; Martin Bergmann
- Book ID
- 106100650
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 556 KB
- Volume
- 112
- Category
- Article
- ISSN
- 1432-119X
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Gap junctions have been reported to play a pivotal role in coordinating embryonic development. Here we report the temporal and spatial pattern of connexin31 that has been found to be coexpressed with connexin43 in preimplantation rat embryos. Connexin31 and connexin43 transcripts are abundant in the
Gap junctional intercellular communication (GJIC) has been proposed as a cellular mechanism for tumour suppression and there is experimental evidence in support of this. If aberrant GJIC contributes to the formation of human breast tumours, one might expect that the connexins (gap junction proteins)
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