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Expression of co-stimulators CD28/B7-1 in peripheral blood of patients with breast cancer

✍ Scribed by Jian Gong, Wen Pan, Chuanjia Yang, Feng Guo, Yunping Sun

Book ID
118796759
Publisher
Springer US
Year
2012
Tongue
English
Weight
127 KB
Volume
136
Category
Article
ISSN
0167-6806

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## Abstract Interleukin‐7‐receptor‐signaling plays a pivotal role in T‐cell development and maintenance of T‐cell memory. We studied IL‐7RΞ± (CD127) expression in PBMCs obtained from patients with breast cancer and examined IL‐7 receptor‐mediated downstream effects defined by STAT5 phosphorylation (