Expression of class I histocompatibility antigens on human T-B lymphoblast hybrids
โ Scribed by David N. Howell; Donna D. Kostyu; Jenny P. -Y. Ting; Peter Cresswell
- Book ID
- 112557870
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 678 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1572-9931
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Regulation of HLA class I and class II antigen expression was studied in hybrids of human T and B lymphoblastoid cell lines (LCL). The T-LCL CEMR.3 expresses no HLA class II antigens. It expresses little total HLA class I antigen and no HLA-B antigens. The B-LCL 721.174 is a radiation-induced varian
We analyzed whether normal human hepatocytes, which normally do not display Class I1 major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases. While both a-and y-interferon induced expression o