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Expression of class I and class II major histocompatibility complex (MHC) antigens on isolated hepatocytes

Book ID
123496808
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
66 KB
Volume
5
Category
Article
ISSN
0168-8278

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Expression of class I and class II major
Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
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We analyzed whether normal human hepatocytes, which normally do not display Class I1 major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases. While both a-and y-interferon induced expression o

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## DIEGO VERGANI' Controversy exists regarding major histocompatibility complex antigen expression on hepatocytes. In this study, hepatocyte expression of class I and I1 major histocompatibility complex antigens was investigated in diseased and normal livers, using indirect immunofluorescent stain

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The expression of gene products of the major histocompatibility complex (MHC) on the cell surface is known to play an important role in immunological responses. While some studies have reported the presence of MHC antigens on hepatocytes, information about specific, sensitive hepatocyte MHC antigen