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Expression of chemokine receptor CXCR4 during chick embryo development

✍ Scribed by Faisal Yusuf; Rizwan Rehimi; Fangping Dai; Beate Brand-Saberi

Publisher
Springer
Year
2005
Tongue
English
Weight
433 KB
Volume
210
Category
Article
ISSN
0340-2061

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## Abstract Binding to a chemokine receptor, either CCR5 or CXCR4, by the gp120 glycoprotein is an essential step in the pathway by which HIV enters host cells. Recently, CCR5 antagonists have been developed that obstruct binding of CCR5 by gp120, thus inhibiting host cell entry. Resistance to such