## Abstract Establishing reuglatory mechanisms that mediate proliferation of osteoblasts while restricting expression of genes asociated with mature bone cell phenotypic properties to postβproliferative cells is fundamental to understanding skeletal development. To gain insight into relationships b
β¦ LIBER β¦
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary cultures of normal diploid osteoblasts
β Scribed by Pockwinse, S.; Conlon, D.; Lian, J.B.; Stein, G.S.
- Book ID
- 121922834
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 179 KB
- Volume
- 13
- Category
- Article
- ISSN
- 8756-3282
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The process of recombinant human bone morphogenetic protein-2 (rhBMP-2)induced endochondral ossification involves 1 ) the proliferation and differentiation of mesenchymal cells into chondroblasts and osteoblasts; 2) the production and maturation of cartilage and bone matrix; and 3 ) the differentiat