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Expression of CD80 and CD86 costimulatory molecules are potential markers for better survival in nasopharyngeal carcinoma

✍ Scribed by Cheng-Shyong Chang; Julia H Chang; Nicholas C Hsu; Hsuan-Yu Lin; Chih-Yuan Chung


Book ID
115011156
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
813 KB
Volume
7
Category
Article
ISSN
1471-2407

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Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,