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Expression of CD4 and chemokine co-receptors on gamma delta T cells renders them susceptible to HIV infection and depletion

✍ Scribed by Mehandru, Saurabh; Poles, Michael A.; Barsoum, Shady; Daly, Jeanine; Sun, Patricia; Ho, David D.; Zhang, Linqi


Book ID
122529891
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
236 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Within the brain, HIV‐1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in contrast to microglia. We aimed to determine whether chemokine receptors play a role in mediating CD4‐independent HIV‐1 entry into astr