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Expression of canine interferon-γ by a recombinant vaccinia virus and its antiviral effect

✍ Scribed by Yoshifumi Nishikawa; Akira Iwata; Atsushi Katsumata; Xuenan Xuan; Hideyuki Nagasawa; Ikuo Igarashi; Kozo Fujisaki; Haruki Otsuka; Takeshi Mikami

Book ID: 117365652
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 231 KB
Volume: 75
Category: Article
ISSN: 0168-1702
DOI: 10.1016/s0168-1702(01)00223-4

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## Abstract Although interferon (IFN)‐α and IFN‐γ have been reported to exhibit a synergistic antiviral effect through the different signaling pathways in vitro, their therapeutic efficacy is not well defined in vivo. The current study was carried out to investigate the combined antiviral effect in