## Abstract ## __Background.__ Despite diagnostic and therapeutic advances in head and neck cancer, the 5βyear survival of patients with laryngeal cancer has not improved in the last 30 years. Several recent studies indicate that specific targets for immunotherapeutic approaches can be useful in t
Expression of cancer testis antigens CT10 (MAGE-C2) and GAGE in gastrointestinal stromal tumors
β Scribed by Ghadban, T.; Perez, D.R.; Vashist, Y.K.; Bockhorn, M.; Koenig, A.M.; El Gammal, A.T.; Izbicki, J.R.; Metzger, U.; Hauswirth, F.; Frosina, D.; Jungbluth, A.A.
- Book ID
- 122216964
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 870 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0748-7983
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## Abstract Cancer testis (CT) antigens are attractive targets for immunotherapy in cancer patients. Immunohistochemistry was used to study the expression of the CT antigens MAGEβC2/CTβ10, MAGEβC1/CTβ7, GAGE, MAGEβA4 and NYβESOβ1 in 146 hepatocellular carcinomas, 13 intrahepatic cholangiocarcinomas
## Abstract Cancer testis antigens (CTAs) have been identified in various tumors as immunological tumor targets. In gastrointestinal stromal tumor (GIST), the prediction of malignant potential remains difficult but is crucial in the era of adjuvant imatinib treatment. Here, we analyzed the impact o
## Abstract Cancer testis antigens (CTAs) are expressed in a variety of malignant tumors but not in any normal adult tissues except germ cells and occasionally placenta. Because of this tumorβassociated pattern of expression, CTAs are regarded as potential vaccine targets. The expression of CTAs in