Expression of Ca2+-binding protein regucalcin in rat brain neurons: inhibitory effect on protein phosphatase activity
โ Scribed by Masayoshi Yamaguchi; Toshie Hamano; Hiroyuki Misawa
- Book ID
- 117501389
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 179 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0361-9230
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## Abstract The role of regucalcin, which is a regulatory protein of calcium signaling, in the regulation of protein phosphatase activity in the nuclei of rat kidney cortex was investigated. Protein phosphatase activity towards phosphotyrosine, phosphoserine, and phosphothreonine was found in the n
The effect of regucalcin, a calcium-binding protein isolated from rat liver cytosol, on Ca2+/calmodulin-dependent cyclic nucleotide (AMP) phosphodiesterase activity in rat liver cytosol was investigated. The addition of Ca2+ (50 microM) and calmodulin 160 U/ml in the enzyme reaction mixture caused a