The bone morphogenetic proteinβhepcidin
The bone morphogenetic proteinβhepcidin axis as a therapeutic target in inflammatory bowel disease
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Lijian Wang; Estela Trebicka; Ying Fu; Shiri Ellenbogen; Charles C. Hong; Jodie
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Article
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2012
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John Wiley and Sons
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English
β 527 KB
Background: A debilitating anemia associated with low serum iron often accompanies inflammatory bowel disease (IBD). Increased production of the iron regulatory hormone hepcidin is implicated in its pathogenesis and may also contribute to the inflammatory process itself. Hepcidin expression is depen