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Expression of Biologically Active Human Interferon Gamma in the Milk of Transgenic Mice Under the Control of the Murine Whey Acidic Protein Gene Promoter

✍ Scribed by Haydar Bagis; Digdem Aktoprakligil; Cagatay Gunes; Sezen Arat; Tolga Akkoc; Gaye Cetinkaya; Orhan Kankavi; Ali Cihan Taskin; Korhan Arslan; Munis Dundar; Vania L. Tsoncheva; Ivan G. Ivanov

Publisher
Springer
Year
2010
Tongue
English
Weight
227 KB
Volume
49
Category
Article
ISSN
0006-2928

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## Abstract Transgenic mice were produced which secreted high levels of bGH into milk. The 6.3‐kb upstream region of the rabbit whey acidic protein (rWAP) gene was linked to the structural part of the bovine growth hormone (bGH) gene, and the chimeric gene was introduced into mouse oocytes. bGH was

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