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Expression of beta-tubulin isotypes in human primary ovarian carcinoma

✍ Scribed by Yoshihiro Ohishi; Yoshinao Oda; Yuji Basaki; Hiroaki Kobayashi; Norio Wake; Michihiko Kuwano; Masazumi Tsuneyoshi

Book ID
113961005
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
289 KB
Volume
105
Category
Article
ISSN
0090-8258

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## Background: Beta-tubulin, the intracellular target of several antimicrotubule agents, is encoded by at least six genes and exists as multiple isotypes with tissue-specific expression. previous in vitro studies indicated that tubulin isotype composition may affect polymerization properties, dynam