Expression of Bcl-2 and Bcl-xL in Cutaneous and Bone Marrow Lesions of Mastocytosis
โ Scribed by Karin Hartmann; Metin Artuc; Stephan E. Baldus; Thomas K. Zirbes; Barbara Hermes; Juergen Thiele; Yoseph A. Mekori; Beate M. Henz
- Book ID
- 117021654
- Publisher
- American Society for Investigative Pathology
- Year
- 2003
- Tongue
- English
- Weight
- 413 KB
- Volume
- 163
- Category
- Article
- ISSN
- 0002-9440
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Background: Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. the authors examined the expression of two related apoptotic inhibitors, bcl-2 and bcl-xl, in pretreatment biopsies from a series of 42 patient
Using western blotting and immunochemical analysis, we investigated alterations in the expression of the apoptosis-related proteins bcl-2, bax, and bcl-X in colonic adenocarcinomas induced by subcutaneous injection of azoxymethane (AOM) (15 mg/kg body weight weekly for 2 wk) into male Sprague-Dawley