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Expression of Bcl-2 and Amplification of c-myc Are Frequent in Basaloid Squamous Cell Carcinomas of the Esophagus

✍ Scribed by Mario Sarbia; Christina Loberg; Marietta Wolter; Jawed Arjumand; Hansjörg Heep; Guido Reifenberger; Helmut E. Gabbert

Book ID
117022592
Publisher
American Society for Investigative Pathology
Year
1999
Tongue
English
Weight
647 KB
Volume
155
Category
Article
ISSN
0002-9440

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✍ Mario Sarbia; Fernando Bittinger; Rainer Porschen; Patrick Verreet; Philipp Dutk 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 587 KB

The bcl-2 proto-oncogene is a known inhibitor of apoptosis and may be an important regulator of tumor growth. In the present study, bcl-2-protein expression was investigated by immunohistochemistry and correlated with prognosis in a series of 150 potentially curatively resected squamous-cell carcino