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Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

✍ Scribed by Shuying Liu; Makiko Umezu-Goto; Mandi Murph; Yiling Lu; Wenbin Liu; Fan Zhang; Shuangxing Yu; L. Clifton Stephens; Xiaojiang Cui; George Murrow; Kevin Coombes; William Muller; Mien-Chie Hung; Charles M. Perou; Adrian V. Lee; Xianjun Fang; Gordon B. Mills


Book ID
113523892
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
34 KB
Volume
16
Category
Article
ISSN
1535-6108

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## Abstract PPP1R13L was initially identified as a protein that binds to the NF‐κB subunit p65/RelA and inhibits its transcriptional activity. It also binds p53 and inhibits its action. One set of experimental findings based on overexpression of PPP1R13L indicates that PPP1R13L blocks apoptosis. An