Expression of apoptosis-related proteins and response to chemoradiotherapy and prognosis in esophageal cancer
โ Scribed by Albert Font; James R. Rigas; Alan Eastman; Vincent A. Memoli; Bernard F. Cole; Sue Hammond; Rafael Rosell
- Publisher
- Springer Milan
- Year
- 2000
- Tongue
- Spanish
- Weight
- 577 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1699-048X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Preoperative chemoradiotherapy is used in locally advanced rectal cancer to reduce local recurrence and improve operability, however a proportion of tumors do not undergo significant regression. Identification of predictive markers of response to chemoradiotherapy would improve patient
## Abstract Formalinโfixed, paraffinโembedded biopsies of 193 women with primary breast cancer followedโup for over 10 years were analysed immunohistochemically for the expression of p53 protein. Altogether, 58% (113/193) of the tumors were positive for p53 protein. Overโexpression of p53 was assoc
Heat-shock protein 27 (hsp27) is one of the small heatshock proteins. Its expression in ovarian-and breast-cancer cell lines has been associated with resistance to cisplatin and doxorubicin. In addition, hsp27 expression appears to facilitate cellular growth, differentiation and motility. In several
## Abstract ## Background Xโlinked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis family of proteins and deregulation of XIAP can result in tumorigenicity. The objective of this study was to evaluate the prognostic significance of XIAP expression in colorectal canc