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Expression of Apoptosis-related Genes in Chronic Cyclosporine Nephrotoxicity in Mice

โœ Scribed by Chul Woo Yang; Gregory R. Faulkner; Ihab M. Wahba; Tracy A. Christianson; Grover C. Bagby; Dong Chan Jin; Hanna E. Abboud; Takeshi F. Andoh; William M. Bennett

Book ID
114423444
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
200 KB
Volume
2
Category
Article
ISSN
1600-6135

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## Background: Long-term treatment with cyclosporine (csa) or tacrolimus (tac) results in chronic nephrotoxicity. transforming growth factor-beta (tgf-beta) and other pro-fibrogenic molecules have been known to contribute to this side effect. a comparison of intrarenal expression of tgf-beta and ot