## BACKGROUND. Overexpression of the multidrug resistance gene (MDR1) product, the MDR1 protein (MDR1), has been associated with poor prognosis in several hematologic malignancies. The significance of MDR1 levels in patients with chronic myeloid leukemia (CML) has not been established. ## METHODS
Expression of apoptosis proteins in chronic myelogenous leukemia : Associations and significance
β Scribed by Farhad Ravandi; Hagop M. Kantarjian; Moshe Talpaz; Susan O'Brien; Stefan Faderl; Francis J. Giles; Debbie Thomas; Jorge Cortes; Michael Andreeff; Zeev Estrov; Mary-Beth Rios; Maher Albitar
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 122 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Circulating blood plasma contains proteinaseβdegraded forms of thrombomodulin that are soluble. We quantitatively assayed the plasma levels of thrombomodulin in 15 patients with chronic myelogenous leukemia (CML) in chronic phase by method of an enzymelinked immunosorbent assay using a
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