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Expression of amyloid precursor protein and presenilin-1 in transgenic mice

✍ Scribed by Christian Czech; Veronique Blanchard; Nicole Clavel; Saliha Moussaoui; Gunter Tremp; Bruno Bonici; Nathalie Touchet; Laurent Pradier; Aventis Pharma


Book ID
117411913
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
184 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract A recent report showed that the accumulation of α‐synuclein (α‐syn) was detected in the brains of one‐third of Alzheimer's disease and Down syndrome patients. However, the relationship between amyloid‐β protein (AΞ²) and α‐syn remains unclear. We analyzed the relation between the mutatio