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Expression of adrenomedullin mRNA in adrenocortical tumors and secretion of adrenomedullin by cultured adrenocortical carcinoma cells

✍ Scribed by Kazuhiro Takahashi; Fumitoshi Satoh; Masahiko Sone; Kazuhito Totsune; Zenei Arihara; Takao Noshiro; Toraichi Mouri; Osamu Murakami

Book ID: 117409278
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 152 KB
Volume: 19
Category: Article
ISSN: 0196-9781
DOI: 10.1016/s0196-9781(98)00128-4

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## Abstract Antiangiogenic therapies are used for advanced clear‐cell renal carcinomas (cRCC), but without curative possibilities, underlining the need for new therapeutic targets. Adrenomedullin (AM), a multifunctional peptide, is highly expressed in several tumors and plays an important role in a