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Expression of active human factor IX in transfected cells

✍ Scribed by Busby, Sharon; Kumar, Ashok; Joseph, Michael; Halfpap, Laurel; Insley, Maggie; Berkner, Kathleen; Kurachi, Kotoku; Woodbury, Richard

Book ID
109739672
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
464 KB
Volume
316
Category
Article
ISSN
0028-0836

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## Abstract ## Background Long‐term expression of the delivered target gene is critical for successful gene therapy. Recently, hepatic control region I (HCR I) originating from the apolipoprotein (apo)C‐I pseudogene was shown to be a critical element for long‐term gene expression in the liver of m