Expression of a truncated secreted form of the mGluR3 subtype of metabotropic glutamate receptor
โ Scribed by Yi Yao; Joseph C.P Koo; James W Wells; David R Hampson
- Book ID
- 116288537
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 267 KB
- Volume
- 319
- Category
- Article
- ISSN
- 0006-291X
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The distribution of metabotropic glutamate receptors 1โฃ (mGluR1โฃ) and mGluR2/3 in the cat retina was studied through the use of preembedding immunocytochemistry for light and electron microscopy. Staining for mGluR1โฃ in the outer plexiform layer was seen in numerous punctate structures that were ide
## Abstract Metabotropic glutamate receptors (mGluRs) are important as candidate therapeutic targets for many neurological disorders. In the present work, the focus has been on the mGluR1 subtype, where agonists have a proconvulsant profile while antagonists exert anticonvulsant activity. Identific