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Expression of a novel gene FAM43B repressing cell proliferation is regulated by DNA methylation in hepatocellular carcinoma cell lines

โœ Scribed by Xiao Xu; Rui-Fang Liu; Bing-Bing Wan; Wen-Ming Xing; Jian Huang; Ze-Guang Han

Publisher
Springer
Year
2011
Tongue
English
Weight
816 KB
Volume
354
Category
Article
ISSN
0300-8177

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## Abstract DNA methyltransferases (DNMTs) are essential for maintenance of aberrant methylation in cancer cells and play important roles in the development of cancers. Unregulated activation of PI3K/Akt pathway is a prominent feature of many human cancers including human hepatocellular carcinoma (