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Expression of 5α-reductase in apocrine carcinoma of the breast and its correlation with clinicopathological aggressiveness

✍ Scribed by Satomi Kasashima; Atsuhiro Kawashima; Satoru Ozaki; Yasuni Nakanuma


Book ID
114729171
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
310 KB
Volume
60
Category
Article
ISSN
0309-0167

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BACKGROUND. Steroid 5a-reductase is essential for the intracellular accumulation of dihydrotestosterone (DHT), which mediates androgen effects on target tissue. METHODS. In the present study, we describe the differential expression and cellular localization of 5a-reductase 1 and 2 isoenzymes in the