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Expression of 5-HT1A receptor mRNA in rat nucleus raphe magnus neurons after peripheral inflammation

✍ Scribed by Yu-Qiu Zhang; Xiu Gao; Zhi-Lan Yang; Ya-Lin Huang; Gen-Cheng Wu


Book ID
113996579
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
599 KB
Volume
887
Category
Article
ISSN
0006-8993

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Serotonin release from dorsal raphe projections in the forebrain is regulated by terminal 5-HT 1B autoreceptors; dysregulation of these receptors may be involved in the pathophysiology of clinical depression. Using in situ hybridization, we have previously reported that fluoxetine reduces 5-HT 1B mR