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Expression, localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals

✍ Scribed by Takashi Matozaki; Yoji Murata; Munemasa Mori; Takenori Kotani; Hideki Okazawa; Hiroshi Ohnishi


Book ID
113528449
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
820 KB
Volume
22
Category
Article
ISSN
0898-6568

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Previous studies in this laboratory have shown that the SH-2 domaincontaining protein tyrosine phosphatase SHP-1 is expressed in CNS glia and functions to modulate cytokine activities in these cells. The present study demonstrates that SHP-1 is expressed within multiple regions of the CNS in vivo, e