## Abstract Antiangiogenic therapies are used for advanced clear‐cell renal carcinomas (cRCC), but without curative possibilities, underlining the need for new therapeutic targets. Adrenomedullin (AM), a multifunctional peptide, is highly expressed in several tumors and plays an important role in a
✦ LIBER ✦
Expression levels of the mitochondrial IAP antagonists Smac/DIABLO and Omi/HtrA2 in clear-cell renal cell carcinomas and their prognostic value
✍ Scribed by Carsten Kempkensteffen; Stefan Hinz; Frank Christoph; Hans Krause; Ahmed Magheli; Mark Schrader; Martin Schostak; Kurt Miller; Steffen Weikert
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 314 KB
- Volume
- 134
- Category
- Article
- ISSN
- 1432-1335
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## Abstract The expression of the inhibitor of apoptosis (IAP) family members cIAP1 and cIAP2 have been shown to be altered in various cancer entities. This study was done to characterize the tumor‐related expression profile of cIAP1 and cIAP2 in patients with renal cell carcinomas (RCC) and to eva